Pharmaceutical companies and consumers alike depend upon the government getting it right in both granting and eliminating market exclusivity. The story of Wellbutrin XL illustrates this point. Originally, Wellbutrin was formulated as an immediate release drug requiring thrice daily administration. A sustained release version introduced in permitted twice daily dosing.
In , an extended release formulation, Wellbutrin XL bupropion HCl extended-release tablets , reduced the dosing to once per day. Wellbutrin XL is dispensed in both mg. FDA News Release.
However, it may not be as common as other side effects such as dizziness, headache, and dry mouth. Wellbutrin increases the activity of norepinephrine and dopamine in the brain. This feeling usually occurs after taking a high dose of bupropion. Wellbutrin inhibits the reuptake of norepinephrine and dopamine. As a result, the drug enhances the activity of these neurotransmitters. Wellbutrin can be used to treat mental health conditions affected by these chemicals in the brain.
Wellbutrin is not approved to treat anxiety. In fact, Wellbutrin may cause anxiety as a side effect. Wellbutrin is primarily used to treat symptoms of depression. Skip to main content Search for a topic or drug. Wellbutrin SR vs. Wellbutrin XL: Differences, similarities, and which is better for you. By Gerardo Sison, Pharm.
Want the best price on Wellbutrin SR? Want the best price on Wellbutrin XL? Top Reads in Drug vs. Toujeo vs Lantus: Main Differences and S Dulera vs Advair: Main Differences and S Suboxone vs Methadone: Main Differences Looking for a prescription?
Search now! Type your drug name. Ticlopidine Clopidogrel. Ritonavir Lopinavir Efavirenz Carbamazepine Phenytoin. Rasagiline Selegiline Isocarboxazid Phenelzine. Levodopa Amantadine. The active ingredient in Wellbutrin XL — bupropion hydrochloride — is believed to act upon norepinephrine and dopamine, two chemicals in the brain known to help regulate different aspects of mood, cognition, and behavior.
Imbalances in these brain chemicals are associated with depressed mood and other symptoms of depression. Bupropion has no clinically significant impact on serotonin, a third brain chemical involved in mood regulation. Pradko, M. The efficacy of bupropion in the treatment of a major depressive episode was established using the immediate-release formulation in two four-week controlled trials of inpatients and one six-week controlled trial of outpatients who met criteria for major depression.
Bupropion is also sometimes used to treat episodes of depression in patients with bipolar disorder manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods and to treat attention deficit hyperactivity disorder ADHD; more difficulty focusing, controlling actions, and remaining still or quiet than other people who are the same age.
Talk to your doctor about the possible risks of using this medication for your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Skip the missed dose and continue your regular dosing schedule. Always allow the full scheduled amount of time to pass between doses of bupropion. Do not take a double dose to make up for a missed one.
Bupropion may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet.
Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking bupropion. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
If you are taking the extended-release tablet, you may notice something that looks like a tablet in your stool. This is just the empty tablet shell and does not mean that you did not get your complete dose of medication. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Generic alternatives may be available.
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